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Sleeping Pill(Alprazolam) Effects, Withdrawal symptomps and Herbal Alternative.

Sleeping Pill(Alprazolam) Effects, Side effects, Withdrawal symptomps and Sleeping Pills Herbal Alternative.

Alprazolam comes under the categroy of Sedative and Hypnotics.  It belongs to a class of Drugs called Benzodiazepines which act on the Brains and nerves  to produce a calming effect.sleeping pills herbal alternatives

Usage of Alprazolam

Alprazolam is used to treat Anxiety and Panic Disorders.

Mechanism of Action of Alprazolam

It works by enhancing the effects of a certain natural chemical in the body (GABA).or increases GABA receptor sensitivity.

These drug stop Anxiety or Panic attack with in 30 to 60 minutes and generally last for 11 to 20 hours. While These drug first seem like a Miracle. but later it is prove that these drugs have various drawbacks. sleeping pills herbal alternatives

Side Effect of Alprazolam

  • Anorexia
  • Nausea
  • Drowsiness
  • Loss of Memory
  • Lose of cordination
  • Slurring of Speech
  • Depression

Duration of treatment and Addiction of Alprazolam

Anti-anxiety medications are designed for short-term use — a few weeks or months at best — since they are highly addictive. After four to six months they generally stop working which is typical of any addictive substance. Users develop a tolerance needing more and more to get the same effect.
While it often takes months for people to develop an addiction, for some it can occur much faster — in as little as a few weeks. Once you are hooked, quitting these medications is really tough. In fact, they are right up there in the “top 10” hardest addictive substances to kick along with heroin and cocaine.sleeping pills herbal alternatives

Withdrawal Symptoms of Alprazolam

If you do decide to quit taking Alprazolam, you can may experience some pretty severe withdrawal symptoms including.sleeping pills herbal alternatives

  • anxiety
  • insomnia,
  • restlessness,
  • muscle tension, and
  • irritability.

Some users experience the following withdrawal symptoms

  • depression
  • nausea
  • blurred vision
  • sweating
  • hallucinations
  • delusions and seizures.

Contraindications of Alprazolam

  • pregnant or Breastfeeding
  • over 65 or prone to addictions.
  • You should never take Alprazolam if you drink alcohol.
  • Acute narrow Angle glaucoma
  • Myasthenia gravis

Care must be taken in

Patient below 18 years of age

Hepatic and Renal Diseases

Stop the drug in case of Paradoxical Excitement, with other CNS depressants.

Dose of Alprazolam

0.25 to 0.5 mg up to three times s day.

Maintenance Dose 1.5 to 4.5 mg daily in divided doses

Herbal alternative of Alprazolam

  1. Noni
  2. Ashwagandha
  3. Tulsi

Noni

Noni works by following Mechanism in Anxiety and Deprresion

  • the extract of Noni fruit showed a preference for binding to GABAa receptors,enhancing the awailability of GABA and Producing Sedative and anti- anxiety effects.
  • Scopoletin present in Noni regulate Harmone serotonin Which help to reduce anxiety and Depression
  • Noni block the two vital Enzyme MAOA and MAOB in brain this action of Noni prevent the decomposition of vital amines.
  • Noni is a rich source of Tryptophan amino acid and tryptophan requires for Serotonin synthesis as we know Serotonin promote sleep.sleeping pills herbal alternatives

Dose 20 to 30 ml per day

Ashwagandha

Ashwagandha reduces Anxiety and Depression without causing drowsiness. it work by following mechanism

  • Ashwagandha increses the level of Mood-boosting neurotransmitter serotonin while decreses the level of stress Harmone cortisol.sleeping pills herbal alternatives

Dose 500 to 1000 mg per day

Tulsi

  • Tulsi decreses the level of stress harmone mainly Cortisol
  • Tulsi also helps in Brain related disorders, including Depression, Memory loss, Insomnia, Migrane etc.sleeping pills herbal alternatives

Dose 15 to 25 leaves

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Disclaimer

Never discontinue a pharmaceutical product without the guidance of a physician.This article is for informational purposes only. Nothing here is intended as or should be substituted for medical advice.

 

References

  1. text book of Pharmacology Kd Tripathi
  2. Quarterly Drug Update book
  3. https://www.ncbi.nlm.nih.gov/m/pubmed/17561385/
  4. https://www.researchgate.net/publication/268415355_Antidepressant_Effects_of_Noni_Fruit_and_its_Active_Principals
  5. http://www.phytochemicals.info/phytochemicals/scopoletin.php

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